Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | RABGGTB | P53611 | 1/20 | 0.33 |
| ▸ | RABGGTA | Q92696 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377787 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7378315 | 0.95 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7378313 | 0.95 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9444930 | 0.87 | HPGD (0.41) | SMN1; SMN2MEN1KMT2AHPGDGPR119 | |
| SCHEMBL7292645 | 0.87 | HPGD (0.41) | SMN1; SMN2MEN1KMT2AHPGDGPR119 | |
| SCHEMBL7379259 | 0.86 | FAAH (0.39) | KMT2AFAAHGPR119 | |
| SCHEMBL7379260 | 0.86 | FAAH (0.39) | KMT2AFAAHGPR119 | |
| SCHEMBL7369150 | 0.86 | BMP1 (0.36) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7369015 | 0.86 | BMP1 (0.36) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7369146 | 0.86 | BMP1 (0.36) | SMN1; SMN2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310015-A2 | Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-05 | — | — | EP | disclosed |