Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.56 |
| ▸ | ITGAV | P06756 | 17/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375575 | 0.87 | ITGB3 (0.52) | ITGB3ITGAVF10ITGA2BCTSL | |
| SCHEMBL7376066 | 0.86 | ITGB3 (0.50) | ITGB3ITGAVF10ITGA2BCTSL | |
| SCHEMBL7379286 | 0.85 | ITGB3 (0.66) | ITGB3ITGAVALBITGA2B | |
| SCHEMBL7379281 | 0.85 | ITGB3 (0.66) | ITGB3ITGAVALBITGA2B | |
| SCHEMBL7380577 | 0.80 | CTSL (0.54) | F10CTSL | |
| SCHEMBL7409607 | 0.80 | ITGB3 (0.47) | ITGB3ITGAVITGA2BCTSLMAPT | |
| SCHEMBL7377898 | 0.80 | CA12 (0.41) | ITGB3ITGAVF10ITGA2BMAPT | |
| SCHEMBL7375597 | 0.80 | CA12 (0.48) | ITGB3ITGAVF10ITGA2BCTSL | |
| SCHEMBL5878537 | 0.79 | ITGB3 (0.86) | ITGB3ITGAVALBITGA2B | |
| SCHEMBL5878533 | 0.79 | ITGB3 (0.86) | ITGB3ITGAVALBITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | disclosed |