Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381790 | 0.85 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL7385262 | 0.84 | PIK3CA (0.44) | ALDH1A1LMNAMAPTKDM4EHPGD | |
| SCHEMBL7385304 | 0.83 | MAPT (0.39) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL7696668 | 0.82 | CA12 (0.48) | ALDH1A1LMNAMAPTCA12CA1 | |
| SCHEMBL7699846 | 0.82 | TSHR (0.46) | ALDH1A1SMN1; SMN2LMNAMAPTCA12 | |
| SCHEMBL7699445 | 0.82 | HSD17B10 (0.36) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL7385154 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAMAPTCA12 | |
| SCHEMBL7385104 | 0.81 | NOTUM (0.40) | ALDH1A1SMN1; SMN2LMNAMAPTCA12 | |
| SCHEMBL7698997 | 0.81 | CYP4F2 (0.41) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL7386364 | 0.81 | CA12 (0.37) | ALDH1A1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998055475-A1 | GUANIDINE DERIVIATIVES AS INHIBITORS OF NA+/H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |