Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | METAP2 | P50579 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521917 | 0.86 | CTNNB1 (0.59) | MAOBDYRK1AMAP4K4CLK2CLK4 | |
| SCHEMBL29365815 | 0.84 | ALDH1A1 (0.56) | MAOBDYRK1AMAP4K4CLK2SRPK1 | |
| SCHEMBL260992 | 0.84 | ALDH1A1 (0.56) | MAOBDYRK1AMAP4K4CLK2SRPK1 | |
| SCHEMBL30194367 | 0.82 | MAPT (0.68) | MAOBDYRK1AMAP4K4CLK2SRPK1 | |
| Hydrochloric Acid SCHEMBL7001071 | 0.82 | ALDH1A1 (0.55) | MAOBDYRK1AMAP4K4CLK2SRPK1 | |
| SCHEMBL475069 | 0.82 | AR (0.63) | MAOBDYRK1AMAP4K4CLK2SRPK1 | |
| SCHEMBL2933207 | 0.82 | MAPT (0.68) | MAOBDYRK1AMAP4K4CLK2SRPK1 | |
| SCHEMBL20187143 | 0.82 | MAOB (0.58) | MAOBDYRK1AMAP4K4CLK2SRPK1 | |
| SCHEMBL29887527 | 0.82 | AR (0.63) | MAOBDYRK1AMAP4K4CLK2SRPK1 | |
| Hydrochloric Acid SCHEMBL31173861 | 0.81 | AR (0.61) | MAOBDYRK1AMAP4K4CLK2SRPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939757-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | Dupont Pharmaceuticals Company (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998043962-A1 | HETEROCYCLIC INTEGRIN INHIBITOR PRODRUGS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-10-08 | — | — | WO | disclosed |
| WO-1997023480-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |