Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3160945 | 0.79 | KDM4E (0.35) | KDM4EPKM | |
| SCHEMBL2522189 | 0.69 | KDM4E (0.38) | KDM4EPKM | |
| SCHEMBL1342079 | 0.67 | KDM4E (0.44) | KDM4E | |
| SCHEMBL9079444 | 0.67 | DPP4 (0.38) | KDM4EPKM | |
| SCHEMBL6218758 | 0.67 | KDM4E (0.40) | KDM4EPKM | |
| Hydrochloric Acid SCHEMBL6243419 | 0.66 | KDM4E (0.39) | KDM4EPKM | |
| SCHEMBL860903 | 0.64 | — | — | |
| SCHEMBL9672400 | 0.64 | KDM4E (0.45) | KDM4EPKM | |
| SCHEMBL6161752 | 0.64 | KDM4E (0.34) | KDM4E | |
| SCHEMBL15334614 | 0.64 | ALDH1A1 (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165500-A1 | AMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES,TNF-ALPHA,AND AGGRECANASE | Du Pont Pharmaceuticals Company (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059874-A1 | NOVEL AMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES, TNF-α, AND AGGRECANASE | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |