Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382683 | 0.93 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1POLBCA12CA1 | |
| SCHEMBL7383054 | 0.91 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1POLBCA12CA1 | |
| SCHEMBL7385220 | 0.90 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1POLBCA12CA1 | |
| SCHEMBL7376284 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1POLBCA12CA1 | |
| SCHEMBL7384937 | 0.84 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1POLBCA12CA1 | |
| SCHEMBL7376732 | 0.82 | ALDH1A1 (0.72) | SMN1; SMN2ALDH1A1POLBCA12CA1 | |
| SCHEMBL7377086 | 0.80 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1POLBCA12CA1 | |
| SCHEMBL7386389 | 0.80 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1POLBCA12CA1 | |
| SCHEMBL7382681 | 0.80 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1POLBCA12CA1 | |
| SCHEMBL17997015 | 0.79 | MMP1 (0.55) | SMN1; SMN2ALDH1A1POLBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889866-A | CARDIOVASCULAR DISEASES, HYPOTENSIVE AGENTS, CONGESTIVE HEART FAILURE | SYNTEX (U.S.A.) INC. (US) | 1989-12-26 | — | — | US | disclosed |