Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376103 | 0.95 | ITGB3 (0.37) | ITGB3ITGA2BDGAT1 | |
| SCHEMBL7376001 | 0.91 | ITGB3 (0.36) | ITGB3ITGA2B | |
| SCHEMBL7381328 | 0.87 | ITGB3 (0.37) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7379177 | 0.87 | SMN1; SMN2 (0.38) | ITGB3ITGA2BDGAT1 | |
| SCHEMBL7378338 | 0.85 | MEN1 (0.40) | DGAT1 | |
| SCHEMBL7375252 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7378411 | 0.82 | ITGB3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL7373934 | 0.82 | ITGB3 (0.36) | ITGB3ITGA2B | |
| SCHEMBL7666232 | 0.81 | ALDH1A1 (0.34) | ITGB3ITGA2BDGAT1ALDH1A1 | |
| SCHEMBL7374634 | 0.81 | ITGB3 (0.38) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131320-A1 | ISOXAZOLINE FIBRINOGEN RECEPTOR ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-09-12 | — | — | EP | claimed |
| WO-2000029407-A1 | ISOXAZOLINE FIBRINOGEN RECEPTOR ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-05-25 | — | — | WO | claimed |
| EP-1131320-A1 | ISOXAZOLINE FIBRINOGEN RECEPTOR ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029407-A1 | ISOXAZOLINE FIBRINOGEN RECEPTOR ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-05-25 | — | — | WO | disclosed |