Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.50 |
| ▸ | ITGAV | P06756 | 3/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373852 | 0.88 | ITGB3 (0.50) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7378811 | 0.86 | PTGER4 (0.48) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7380122 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7379531 | 0.84 | ITGB3 (0.56) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7373419 | 0.83 | ITGB3 (0.66) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7378623 | 0.82 | SMN1; SMN2 (0.58) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7376558 | 0.82 | ITGB3 (0.70) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7372597 | 0.81 | KCNK3 (0.50) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7377637 | 0.81 | MAPT (0.55) | ITGB3ITGA2BSMN1; SMN2LMNAMAPT | |
| SCHEMBL7861970 | 0.80 | ITGB3 (0.76) | ITGB3ITGA2BITGAVITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |