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SCHEMBL7378908

SCHEMBL7378908

CSc1sc(C(=N)N)cc1N(S(=O)(=O)c1cccc2ccccc12)S(=O)(=O)c1cccc2ccccc12.CSc1sc(C(=N)N)cc1NS(=O)(=O)c1cccc2ccccc12.CSc1sc(C(=N)N)cc1NS(=O)(=O)c1ccccc1C

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ C1S P09871 19/20 0.45
▸ PLAU P00749 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7380715 0.98 C1S (0.45) C1SPLAU
SCHEMBL6923767 0.87 C1S (0.54) C1SPLAU
SCHEMBL6926375 0.87 C1S (0.54) C1SPLAU
SCHEMBL6925630 0.85 C1S (0.55) C1SPLAU
SCHEMBL7380066 0.84 C1S (0.49) C1SPLAU
SCHEMBL6926809 0.83 C1S (0.55) C1SPLAU
SCHEMBL7375841 0.74 C1S (0.54) C1S
SCHEMBL7240685 0.74 C1S (0.56) C1SPLAU
SCHEMBL7382625 0.73 C1S (0.52) C1SPLAU
SCHEMBL7242120 0.71 C1S (0.65) C1SPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1150979-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2001-11-07 — — EP disclosed
WO-2000047578-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2000-08-17 — — WO disclosed