Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825248 | 0.88 | GAA (0.51) | KDM4EGAAHSD17B10TSHRALDH1A1 | |
| SCHEMBL3488684 | 0.85 | GAA (0.55) | KDM4EGAAHSD17B10TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL8838006 | 0.83 | GNAI3 (0.54) | GNAI3GNAO1GNAI1KDM4EGAA | |
| SCHEMBL23820743 | 0.81 | GAA (0.46) | KDM4EGAAHSD17B10TSHRALDH1A1 | |
| SCHEMBL1018964 | 0.79 | GNAI3 (0.64) | GNAI3GNAO1GNAI1HSD17B10TSHR | |
| SCHEMBL23934142 | 0.78 | GAA (0.44) | KDM4EGAAHSD17B10TSHRALDH1A1 | |
| SCHEMBL6219131 | 0.78 | GNAI3 (0.55) | GNAI3GNAO1GNAI1HSD17B10TSHR | |
| SCHEMBL13848940 | 0.78 | GAA (0.48) | GNAI3GNAO1GNAI1GAATSHR | |
| SCHEMBL2036836 | 0.77 | EPHX2 (0.47) | GNAI3GNAO1GNAI1KDM4EGAA | |
| SCHEMBL13006886 | 0.77 | GAA (0.49) | KDM4EGAAHSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |