Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.64 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.64 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | GABRE | P78334 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6803030 | 0.98 | GNAI3 (0.67) | GNAI3GNAO1GNAI1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8421540 | 0.98 | GNAI3 (0.67) | GNAI3GNAO1GNAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3935665 | 0.88 | GNAI3 (0.51) | GNAI3GNAO1GNAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12574191 | 0.88 | GNAI3 (0.51) | GNAI3GNAO1GNAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1678458 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL2015546 | 0.86 | GNAI3 (0.54) | GNAI3GNAO1GNAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1438745 | 0.86 | GNAI3 (0.73) | GNAI3GNAO1GNAI1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2015550 | 0.86 | GNAI3 (0.54) | GNAI3GNAO1GNAI1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28988641 | 0.84 | — | — | |
| SCHEMBL25045022 | 0.83 | GNAI3 (0.55) | GNAI3GNAO1GNAI1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057964-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2016-08-24 | — | — | EP | claimed |
| WO-2015057659-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | claimed |
| US-20040063701-A1 | Piperidine derivatives and anti-platelet agents containing the same | AJINOMOTO CO., INC (JP) | 2004-04-01 | — | — | US | claimed |
| US-20020147195-A1 | Piperidine derivatives and anti-platelet agents containing the same | AJINOMOTO CO., INC. (JP) | 2002-10-10 | — | — | US | claimed |
| US-20020019533-A1 | PIPERIDINE DERIVATIVES AND ANTI-PLATELET AGENTS CONTAINING THE SAME | MAKINO SHINGO (JP) | 2002-02-14 | — | — | US | claimed |
| EP-0682015-B1 | Piperidine derivates and anti-platelet agents containing the same | AJINOMOTO KK (JP) | 2001-08-22 | — | — | EP | claimed |
| CN-118146234-A | 6,5,7,6-Tetracyclic derivatives, preparation method and application thereof | 浙江我武翼方药业有限公司 | 2024-06-07 | — | — | CN | disclosed |
| EP-3873600-B9 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2024-02-14 | — | — | EP | disclosed |
| US-20230303514-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2023-09-28 | — | — | US | disclosed |
| EP-3873599-B1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-09-27 | — | — | EP | disclosed |
| EP-3873600-B1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-09-20 | — | — | EP | disclosed |
| CN-110105346-B | Optionally substituted quinoline compounds | 卫材R&D管理有限公司 | 2023-03-10 | — | — | CN | disclosed |
| WO-2023018648-A1 | PHENOL DERIVATIVES FOR USE IN THE MODULATION OF BRM | GENENTECH, INC. (US) | 2023-02-16 | — | — | WO | disclosed |
| US-20020037906-A1 | Therapeutic agent for intermittent claudication | AJINOMOTO CO., INC. (JP) | 2002-03-28 | — | — | US | disclosed |
| EP-1155693-A1 | INTERMITTENT CLAUDICATION REMEDIES | Ajinomoto Co., Inc. (JP) | 2001-11-21 | — | — | EP | disclosed |
| EP-1155693-A1 | INTERMITTENT CLAUDICATION REMEDIES | Ajinomoto Co., Inc. (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-6262076-B1 | PIPERIDINE DERIVATIVES, E.G., 1-FORMYL-N-(2-(4-(5H-DIBENZO(A, D)CYCLOHEPTENE-5-YLIDEN)-1-PIPERIDINYL))ETHYLISONIPECOTAMIDE | AJINOMOTO CO., INC. (JP) | 2001-07-17 | — | — | US | disclosed |
| US-5932593-A | ANTISEROTONIN AGENT | AJINOMOTO CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0168812-A1 | 4-Amino-2-phenyl quinolines, methods and intermediates for their preparation and medicaments containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-01-22 | — | — | EP | disclosed |
| US-4560692-A | ANTICONVULSANTS OR ANXIOLYTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1985-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303514-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | TLR7, TLR8, TLR9 | GNAI3 483/4885GNAO1 240/4885GNAI1 214/4885 |
| US-20020019533-A1 | PIPERIDINE DERIVATIVES AND ANTI-PLATELET AGENTS CONTAINING THE SAME | HTR2A, PDGFRA, PDGFRB | GNAI3 1321/4885GNAO1 2039/4885GNAI1 1353/4885 |
| US-20020147195-A1 | Piperidine derivatives and anti-platelet agents containing the same | HTR2A, PDGFRA, PDGFRB | GNAI3 1321/4885GNAO1 2039/4885GNAI1 1353/4885 |
| US-20020037906-A1 | Therapeutic agent for intermittent claudication | PPIP5K2, QDPR, DLD | GNAI3 1022/4885GNAO1 759/4885GNAI1 515/4885 |
| US-20040063701-A1 | Piperidine derivatives and anti-platelet agents containing the same | HTR2A, PDGFRA, PDGFRB | GNAI3 1321/4885GNAO1 2039/4885GNAI1 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.