Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 16/20 | 0.58 |
| ▸ | F2 | P00734 | 9/20 | 0.58 |
| ▸ | F10 | P00742 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390988 | 1.00 | F7 (0.58) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL7347363 | 0.85 | ITGB3 (0.64) | F7F2ITGB3ITGA2B | |
| SCHEMBL15329776 | 0.84 | NPC1 (0.57) | — | |
| SCHEMBL19473725 | 0.80 | FPR2 (0.57) | — | |
| SCHEMBL13714709 | 0.79 | F2 (0.61) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL4426386 | 0.78 | F7 (0.64) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL9385559 | 0.77 | ITGB3 (0.52) | F2F10PRSS1ST14ITGB3 | |
| SCHEMBL4553738 | 0.77 | F2 (0.77) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL7385468 | 0.76 | MAPT (0.55) | — | |
| SCHEMBL9394421 | 0.76 | CASR (0.47) | F7F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624956-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5475025-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1994017041-A1 | AMIDINOPHENYL SUBSTITUTED UREA, THIOUREA OR GUANIDINO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | disclosed |
| US-5314902-A | Thioureas and guanidine compounds, anticoagulants | MONSANTO COMPANY (US) | 1994-05-24 | — | — | US | disclosed |