Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.54 |
| ▸ | CTSL | P07711 | 9/20 | 0.46 |
| ▸ | CTSS | P25774 | 7/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372044 | 0.83 | CTSK (0.58) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7342176 | 0.79 | CTSK (0.58) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7372135 | 0.77 | CTSK (0.67) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580683 | 0.72 | CTSK (0.89) | CTSKCTSLCTSSCTSBMAPK1 | |
| SCHEMBL6165550 | 0.71 | KMT2A (0.66) | CTSKCTSLCTSSCTSBMAPK1 | |
| SCHEMBL6165558 | 0.71 | KMT2A (0.66) | CTSKCTSLCTSSCTSBMAPK1 | |
| SCHEMBL6165554 | 0.71 | KMT2A (0.66) | CTSKCTSLCTSSCTSBMAPK1 | |
| SCHEMBL14561117 | 0.71 | CTSK (0.51) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6581928 | 0.70 | CTSK (0.82) | CTSKCTSLCTSSCTSBMAPK1 | |
| SCHEMBL7382759 | 0.70 | CTSK (0.57) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997016177-A9 | METHOD OF INHIBITING CATHEPSIN K | — | 1997-07-24 | — | — | WO | disclosed |