Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 7/20 | 0.54 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577961 | 0.89 | CTSK (0.51) | CTSKCTSBCTSLCTSSTAOK1 | |
| SCHEMBL6580526 | 0.88 | CTSK (0.51) | CTSKCTSBCTSLCTSSTAOK1 | |
| SCHEMBL6578151 | 0.86 | CTSK (0.56) | CTSKCTSBCTSLCTSSTAOK1 | |
| SCHEMBL6580372 | 0.85 | CTSK (0.75) | CTSKCTSBCTSLCTSS | |
| SCHEMBL6578144 | 0.85 | CTSK (0.55) | CTSKCTSBCTSLCTSSTAOK1 | |
| SCHEMBL6582647 | 0.85 | CTSK (0.54) | CTSKCTSBCTSLCTSSTAOK1 | |
| SCHEMBL6580725 | 0.84 | CTSK (0.47) | CTSKCTSBCTSLCTSS | |
| SCHEMBL6580618 | 0.84 | CTSK (0.54) | CTSKCTSBCTSLCTSSTAOK1 | |
| Lithium Ion SCHEMBL6579977 | 0.82 | CTSK (0.52) | CTSKCTSBCTSLCTSSTAOK1 | |
| SCHEMBL6580334 | 0.79 | CTSL (0.50) | CTSKCTSBCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-A4 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 1999-10-13 | — | — | EP | claimed |
| EP-0936912-A1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-25 | — | — | EP | claimed |
| WO-1998005336-A1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-12 | — | — | WO | claimed |