Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381283 | 0.82 | MAPT (0.41) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL6926332 | 0.71 | KMT2A (0.42) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL5294889 | 0.69 | GAA (0.67) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL1196343 | 0.69 | NOS3 (0.47) | MAPTMEN1KMT2ATDP1HPGD | |
| SCHEMBL6920258 | 0.68 | MEN1 (0.46) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL6921465 | 0.68 | ALDH1A1 (0.43) | MAPTGAAMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4496671 | 0.67 | NOS3 (0.46) | MAPTMEN1KMT2ATDP1HPGD | |
| SCHEMBL15114279 | 0.67 | GAA (0.64) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL18235948 | 0.67 | MAPT (0.55) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL18235922 | 0.66 | GAA (0.62) | MAPTGAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002050056-A1 | BENZYLAMINE DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-06-27 | — | — | WO | disclosed |