Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | PDE5A | O76074 | 4/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543144 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MEN1BLMKMT2ATSHR | |
| SCHEMBL3207749 | 0.76 | LMNA (0.32) | ALDH1A1PDE4BMEN1BLMKMT2A | |
| SCHEMBL11662894 | 0.76 | PDE5A (0.36) | ALDH1A1PDE5APDE4BMIFMEN1 | |
| SCHEMBL10359945 | 0.72 | PDE4B (0.50) | ALDH1A1PDE5APDE4BMIFMEN1 | |
| SCHEMBL13851134 | 0.71 | ALDH1A1 (0.38) | ALDH1A1PDE4BPDE3ATYRLMNA | |
| SCHEMBL21067238 | 0.68 | MEN1 (0.41) | ALDH1A1MEN1BLMKMT2ATSHR | |
| SCHEMBL7377607 | 0.68 | MIF (0.40) | ALDH1A1PDE5APDE4BMIFMEN1 | |
| SCHEMBL3228099 | 0.68 | PDE4B (0.53) | ALDH1A1PDE5APDE4BPDE3ATYR | |
| SCHEMBL25803194 | 0.68 | PDE5A (0.36) | ALDH1A1PDE5APDE4BMIFMEN1 | |
| SCHEMBL27351226 | 0.67 | MAP4K4 (0.38) | ALDH1A1PDE5APDE4BMIFMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368343-A2 | Ameliorating composition for dysmnesia | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1990-05-16 | — | — | EP | disclosed |