Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.59 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.52 |
| ▸ | PDE4A | P27815 | 2/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388684 | 0.94 | GPR119 (0.52) | GPR119CHEK2PDE4DPDE4APDE4B | |
| SCHEMBL7389633 | 0.94 | GPR119 (0.52) | GPR119CHEK2PDE4DPDE4APDE4B | |
| SCHEMBL1375168 | 0.89 | GPR119 (0.61) | GPR119CHEK2PDE4DPDE4APDE4B | |
| SCHEMBL7392069 | 0.85 | CHEK2 (0.55) | GPR119CHEK2KMT2A | |
| SCHEMBL1376438 | 0.84 | PDE4D (0.56) | GPR119CHEK2PDE4DPDE4APDE4B | |
| SCHEMBL1375476 | 0.84 | GPR119 (0.60) | GPR119CHEK2PDE4DPDE4APDE4B | |
| SCHEMBL20046236 | 0.83 | GPR119 (0.55) | GPR119CHEK2PDE4DPDE4APDE4B | |
| SCHEMBL6192490 | 0.82 | GPR119 (0.62) | GPR119CHEK2PDE4DPDE4APDE4B | |
| SCHEMBL1649132 | 0.82 | GPR119 (0.64) | GPR119CHEK2PDE4DPDE4APDE4B | |
| SCHEMBL3345205 | 0.82 | GPR119 (0.64) | GPR119CHEK2PDE4DPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962695-A | ANTICOAGULANT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5620991-A | ANTICOAGULANTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |