Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389633 | 1.00 | GPR119 (0.52) | GPR119USP30CHEK2PDE4DPDE4A | |
| SCHEMBL7380480 | 0.94 | GPR119 (0.59) | GPR119CHEK2PDE4DPDE4APDE4B | |
| SCHEMBL7379041 | 0.88 | GPR119 (0.52) | GPR119USP30CHEK2PDE4DPDE4A | |
| SCHEMBL1375168 | 0.84 | GPR119 (0.61) | GPR119USP30CHEK2PDE4DPDE4A | |
| SCHEMBL5544755 | 0.83 | USP30 (0.58) | GPR119USP30CHEK2KMT2APIK3CD | |
| SCHEMBL5545000 | 0.83 | USP30 (0.58) | GPR119USP30CHEK2KMT2APIK3CD | |
| SCHEMBL240368 | 0.83 | USP30 (0.58) | GPR119USP30CHEK2KMT2APIK3CD | |
| SCHEMBL6188750 | 0.83 | GPR119 (0.54) | GPR119USP30PIK3CDPOLB | |
| SCHEMBL7386960 | 0.83 | GPR119 (0.52) | GPR119USP30CHEK2PIK3CD | |
| SCHEMBL3911512 | 0.83 | GPR119 (0.52) | GPR119USP30CHEK2KMT2APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962695-A | ANTICOAGULANT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5866577-A | AN ANTICOAGULANT AGENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5620991-A | ANTICOAGULANTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |