Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157945 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NPSR1CYP3A4CYP2D6 | |
| SCHEMBL157944 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NPSR1CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL23827956 | 0.98 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2NPSR1CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL20912734 | 0.98 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2NPSR1CYP3A4CYP2D6 | |
| SCHEMBL22322164 | 0.98 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2NPSR1CYP3A4CYP2D6 | |
| SCHEMBL147120 | 0.95 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2NPSR1CYP3A4CYP2D6 | |
| SCHEMBL919280 | 0.95 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2NPSR1CYP3A4CYP2D6 | |
| SCHEMBL147119 | 0.95 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2NPSR1CYP3A4CYP2D6 | |
| SCHEMBL16635360 | 0.93 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2NPSR1CYP3A4CYP2D6 | |
| SCHEMBL38557 | 0.93 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2NPSR1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922054-B1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET (HU) | 2002-08-14 | — | — | EP | disclosed |
| US-6235707-B1 | Anticoagulant peptidyl-arginine aldehyde derivatives | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2001-05-22 | — | — | US | disclosed |
| EP-0922054-A1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET KFT. (HU) | 1999-06-16 | — | — | EP | disclosed |
| WO-1997046576-A1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | Gyógyszerkutató Intézet Kft. (HU) | 1997-12-11 | — | — | WO | disclosed |