Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 3/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412455 | 1.00 | SOAT1 (0.44) | SOAT1ALDH1A1METAP2SLC1A3SLC1A2 | |
| SCHEMBL7377846 | 1.00 | SOAT1 (0.44) | SOAT1ALDH1A1METAP2SLC1A3SLC1A2 | |
| SCHEMBL7381317 | 0.97 | SOAT1 (0.44) | SOAT1ALDH1A1METAP2SLC1A3SLC1A2 | |
| SCHEMBL7379023 | 0.97 | SOAT1 (0.44) | SOAT1ALDH1A1METAP2SLC1A3SLC1A2 | |
| SCHEMBL7380225 | 0.87 | METAP2 (0.37) | METAP2SLC1A3SLC1A2SLC1A1REN | |
| SCHEMBL7373721 | 0.87 | METAP2 (0.37) | METAP2SLC1A3SLC1A2SLC1A1REN | |
| SCHEMBL28785091 | 0.86 | METAP2 (0.42) | METAP2SLC1A3SLC1A2SLC1A1REN | |
| SCHEMBL1066592 | 0.86 | METAP2 (0.42) | METAP2SLC1A3SLC1A2SLC1A1REN | |
| SCHEMBL20543740 | 0.83 | METAP2 (0.45) | ALDH1A1METAP2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7525607 | 0.83 | CTSK (0.36) | METAP2SLC1A3SLC1A2SLC1A1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922054-B1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET (HU) | 2002-08-14 | — | — | EP | disclosed |
| US-6235707-B1 | Anticoagulant peptidyl-arginine aldehyde derivatives | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2001-05-22 | — | — | US | disclosed |
| EP-0922054-A1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET KFT. (HU) | 1999-06-16 | — | — | EP | disclosed |
| WO-1997046576-A1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | Gyógyszerkutató Intézet Kft. (HU) | 1997-12-11 | — | — | WO | disclosed |