Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 5/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385395 | 0.86 | GPR119 (0.56) | GPR119F10F2 | |
| SCHEMBL7387812 | 0.82 | GPR119 (0.41) | GPR119 | |
| SCHEMBL8472255 | 0.82 | GPR119 (0.39) | GPR119PIK3CDARMCL1GRIN1 | |
| SCHEMBL7385828 | 0.81 | GPR119 (0.50) | GPR119F10F2PIK3CD | |
| Hydrochloric Acid SCHEMBL7386612 | 0.80 | F10 (0.43) | F10F2ACACBGRIN1GRIN2B | |
| SCHEMBL7387070 | 0.79 | GPR119 (0.34) | GPR119F10F2 | |
| SCHEMBL7390384 | 0.77 | F10 (0.40) | F10F2ACACB | |
| SCHEMBL7379068 | 0.77 | F10 (0.51) | GPR119F10F2MCL1 | |
| SCHEMBL7379072 | 0.77 | GPR119 (0.37) | GPR119F10F2MCL1 | |
| SCHEMBL7385008 | 0.77 | F10 (0.47) | GPR119F10F2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |