Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 4/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 15/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385010 | 0.93 | GPR119 (0.37) | GPR119MCL1BCL2BCL2L1 | |
| SCHEMBL7379068 | 0.86 | F10 (0.51) | GPR119F10F2MCL1 | |
| SCHEMBL7384317 | 0.85 | GPR119 (0.49) | GPR119F10F2 | |
| SCHEMBL7387970 | 0.81 | GPR119 (0.41) | GPR119 | |
| SCHEMBL7391175 | 0.81 | HRH3 (0.41) | F10F2 | |
| SCHEMBL7385008 | 0.79 | F10 (0.47) | GPR119F10F2MCL1 | |
| SCHEMBL7388570 | 0.79 | F10 (0.41) | GPR119F10F2 | |
| SCHEMBL7380630 | 0.77 | GPR119 (0.39) | GPR119F10F2MCL1 | |
| SCHEMBL7387009 | 0.77 | F10 (0.38) | GPR119F10F2 | |
| SCHEMBL7390197 | 0.75 | TP53 (0.35) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620991-A | ANTICOAGULANTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |