Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383945 | 0.87 | ACHE (0.52) | ACHEMAPTTP53 | |
| Water SCHEMBL7385385 | 0.86 | ACHE (0.51) | ACHEMAPTTP53 | |
| Water SCHEMBL7385383 | 0.86 | ACHE (0.51) | ACHEMAPTTP53 | |
| SCHEMBL7380712 | 0.81 | ACHE (0.56) | ACHEALDH1A1 | |
| SCHEMBL7384764 | 0.77 | ACHE (0.54) | ACHE | |
| SCHEMBL7380828 | 0.74 | HTT (0.45) | ACHEMAPTTP53RAB9ASMN1; SMN2 | |
| SCHEMBL7377027 | 0.72 | ACHE (0.55) | ACHE | |
| SCHEMBL10573396 | 0.70 | ACHE (0.55) | ACHE | |
| SCHEMBL7386411 | 0.70 | ACHE (0.57) | ACHE | |
| SCHEMBL10569871 | 0.69 | ACHE (0.48) | ACHETDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851536-A | ANTIFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-07-25 | — | — | US | claimed |
| US-4970316-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-11-13 | — | — | US | disclosed |
| US-4851536-A | ANTIFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |