Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11002356 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MAPK1TDP1POLBTSHR | |
| SCHEMBL14991432 | 0.80 | ALDH1A1 (0.72) | ALDH1A1MAPK1TDP1POLBTSHR | |
| SCHEMBL6443452 | 0.78 | ALDH1A1 (0.70) | ALDH1A1MAPK1TDP1POLBTSHR | |
| SCHEMBL6443447 | 0.78 | ALDH1A1 (0.70) | ALDH1A1MAPK1TDP1POLBTSHR | |
| SCHEMBL22982168 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MAPK1TDP1POLBTSHR | |
| SCHEMBL8965092 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPK1TDP1POLBTSHR | |
| SCHEMBL4624403 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPK1TDP1POLBTSHR | |
| SCHEMBL10998807 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPK1TDP1POLBTSHR | |
| SCHEMBL11002726 | 0.77 | ALDH1A1 (0.68) | ALDH1A1MAPK1TDP1POLBTSHR | |
| SCHEMBL3785783 | 0.77 | ALDH1A1 (0.68) | ALDH1A1MAPK1TDP1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019034-A2 | ANTIOXIDANT ENHANCEMENT OF THERAPY FOR HYPERPROLIFERATIVE CONDITIONS | Atherogenics, Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999001118-A9 | ANTIOXIDANT ENHANCEMENT OF THERAPY FOR HYPERPROLIFERATIVE CONDITIONS | ATHEROGENICS INC (US) | 1999-05-20 | — | — | WO | disclosed |
| WO-1999001118-A2 | ANTIOXIDANT ENHANCEMENT OF THERAPY FOR HYPERPROLIFERATIVE CONDITIONS | ATHEROGENICS, INC. (US) | 1999-01-14 | — | — | WO | disclosed |