Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 14/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 12/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389752 | 0.96 | ITGA4 (0.54) | ITGA4ITGB1ITGB7CTSA | |
| SCHEMBL7423227 | 0.94 | ITGA4 (0.53) | ITGA4ITGB1ITGB7SMN1; SMN2CTSA | |
| SCHEMBL7421221 | 0.91 | ITGA4 (0.55) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7427083 | 0.89 | ITGB1 (0.55) | ITGA4ITGB1ITGB7SMN1; SMN2 | |
| SCHEMBL7427051 | 0.89 | ITGB1 (0.55) | ITGA4ITGB1ITGB7SMN1; SMN2 | |
| SCHEMBL7393025 | 0.89 | ITGA4 (0.55) | ITGA4ITGB1ITGB7SMN1; SMN2 | |
| SCHEMBL7419999 | 0.88 | ITGA4 (0.50) | ITGA4ITGB1ITGB7SMN1; SMN2CTSA | |
| SCHEMBL7423673 | 0.88 | ITGB1 (0.49) | ITGA4ITGB1ITGB7CTSA | |
| SCHEMBL7648745 | 0.87 | ITGA4 (0.52) | ITGA4ITGB1ITGB7SMN1; SMN2 | |
| SCHEMBL7651105 | 0.87 | ITGB1 (0.54) | ITGA4ITGB1ITGB7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |