Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 18/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 12/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648845 | 0.96 | ITGA4 (0.54) | ITGA4ITGB1SMN1; SMN2ITGB7 | |
| SCHEMBL7421234 | 0.94 | ITGA4 (0.51) | ITGA4ITGB1SMN1; SMN2ITGB7 | |
| SCHEMBL7388976 | 0.91 | ITGA4 (0.55) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7425519 | 0.89 | ITGA4 (0.54) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7422723 | 0.89 | ITGA4 (0.54) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7389985 | 0.89 | ITGA4 (0.57) | ITGA4ITGB1SMN1; SMN2 | |
| SCHEMBL7588650 | 0.88 | ITGA4 (0.50) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7427395 | 0.88 | ITGA4 (0.52) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7387429 | 0.88 | ITGA4 (0.49) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7380743 | 0.87 | ITGA4 (0.52) | ITGA4ITGB1SMN1; SMN2ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |