Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 4/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380755 | 0.84 | KMT2A (0.43) | DDB1CRBNGAAHSD17B10TP53 | |
| SCHEMBL9249468 | 0.74 | MAP3K14 (0.35) | DDB1CRBNGAAMEN1KMT2A | |
| SCHEMBL7385158 | 0.71 | HSD17B10 (0.43) | DDB1CRBNGAAHSD17B10TP53 | |
| SCHEMBL7270134 | 0.71 | MAP3K14 (0.33) | DDB1CRBNMEN1KMT2A | |
| SCHEMBL7378937 | 0.71 | KCNQ2 (0.40) | GAAHSD17B10TP53MEN1KMT2A | |
| SCHEMBL11154702 | 0.71 | ALDH1A1 (0.43) | ALOX15GAAHSD17B10TP53MEN1 | |
| SCHEMBL7379863 | 0.70 | MEN1 (0.44) | GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL7381326 | 0.70 | MEN1 (0.44) | GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL7384140 | 0.69 | TP53 (0.39) | DDB1CRBNTP53GPBAR1SLC6A2 | |
| SCHEMBL7383592 | 0.68 | CHRM2 (0.39) | DDB1CRBNMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | claimed |
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | disclosed |