SCHEMBL7380872

SCHEMBL7380872

O=Cc1cccc(S(=O)(=O)Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
TDP1 Q9NUW8 2/20 0.48
HSD17B10 Q99714 1/20 0.48
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA9 Q16790 2/20 0.47
CA12 O43570 1/20 0.47
UNG P13051 1/20 0.42
CYP2A6 P11509 1/20 0.41
NAT1 P18440 1/20 0.39
KDM4E B2RXH2 2/20 0.39
PTGS2 P35354 1/20 0.39
RAB9A P51151 1/20 0.39
SRC P12931 1/20 0.38
TRIM24 O15164 1/20 0.37
TRIM33 Q9UPN9 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31604493 0.83 ALDH1A1 (0.50) ALDH1A1CA1CA2CA9CA12
SCHEMBL6853269 0.83 ALDH1A1 (0.50) ALDH1A1CA1CA2CA9CA12
SCHEMBL7377333 0.82 TDP1 (0.46) ALDH1A1TDP1HSD17B10CA1CA2
SCHEMBL16712226 0.81 CA1 (0.49) ALDH1A1CA1CA2CA9CA12
SCHEMBL56599 0.79 ALDH1A1 (0.65) ALDH1A1TDP1HSD17B10CA1CA2
SCHEMBL879394 0.79 CA2 (0.66) ALDH1A1CA1CA2CA9CA12
SCHEMBL1373920 0.79 ALDH1A1 (0.53) ALDH1A1TDP1HSD17B10CA1CA2
SCHEMBL41941 0.79 CA12 (0.47) ALDH1A1CA1CA2CA9CA12
SCHEMBL30402657 0.79 CA12 (0.47) ALDH1A1CA1CA2CA9CA12
SCHEMBL17161329 0.79 CA2 (0.47) ALDH1A1CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0154811-A2 Coupling agents between mineral fillers and polymers Plüss-Staufer AG (CH) 1985-09-18 EP claimed
WO-1985003505-A2 COUPLING AGENT BETWEEN MINERAL FILLERS AND POLYMERS PLÜSS-STAUFER AG (CH) 1985-08-15 WO claimed
WO-2009100168-A1 DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS GLAXO GROUP LIMITED (GB) 2009-08-13 WO disclosed
US-6214882-B1 Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof SYNTHELABO (FR) 2001-04-10 US disclosed
EP-0842148-B1 BENZENESULPHONAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USES THEREOF SANOFI SYNTHELABO (FR) 2000-12-20 EP disclosed
EP-0581939-B1 N-SULPHONYL-2-OXOINDOLE DERIVATIVES HAVING AFFINITY FOR VASOPRESSIN AND/OR OCYTOCIN RECEPTORS SANOFI SA (FR) 1999-06-02 EP disclosed
CN-1198735-A Benzenesulfonamide derivatives, their preparation and their use in medicine SYNTHELABO (FR) 1998-11-11 CN disclosed
EP-0842148-A1 BENZENESULPHONAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USES THEREOF SYNTHELABO (FR) 1998-05-20 EP disclosed
WO-1997006136-A1 BENZENESULPHONAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USES THEREOF SYNTHELABO (FR) 1997-02-20 WO disclosed
EP-0581939-A1 N-SULPHONYL-2-OXOINDOLE DERIVATIVES HAVING AFFINITY FOR VASOPRESSIN AND/OR OCYTOCIN RECEPTORS SANOFI (FR) 1994-02-09 EP disclosed
WO-1993015051-A1 N-SULPHONYL-2-OXOINDOLE DERIVATIVES HAVING AFFINITY FOR VASOPRESSIN AND/OR OCYTOCIN RECEPTORS ELF SANOFI (FR) 1993-08-05 WO disclosed
EP-0154811-A2 Coupling agents between mineral fillers and polymers Plüss-Staufer AG (CH) 1985-09-18 EP disclosed
US-4163810-A Ultraviolet curable powder paints SCM CORPORATION (US) 1979-08-07 US disclosed
US-4129488-A Ultraviolet curable epoxy-polyester powder paints SCM CORPORATION (US) 1978-12-12 US disclosed
US-4105518-A POLYMER CONTAINING ACRYLYL, ACRYLAMIDE OR ALLYL UNSATURATED GROUPS, REACTED WITH SECONDARY AMINE AND NEUTRALIZED, SENSITIZER SCM CORPORATION (US) 1978-08-08 US disclosed
US-4052280-A PHOTOSENTIZER IN BACKBONE OF POLYMER SCM CORPORATION (US) 1977-10-04 US disclosed
US-4040925-A PAINTS; CHEMICALLY BONDED ULTRAVIOLET SENSITIZER SCM CORPORATION (US) 1977-08-09 US disclosed
US-4039414-A ACRYLYL, ACRYLAMIDE, OR ALLYL POLYMERS, BENZALDEHYDE SENSITIZER SCM CORPORATION (US) 1977-08-02 US disclosed