Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720858 | 0.89 | RAB9A (0.52) | MEN1KMT2AMAPTNPC1NFKB1 | |
| SCHEMBL6724361 | 0.88 | RXFP1 (0.60) | RXFP1TRPV1MEN1KMT2AMAPT | |
| SCHEMBL6716936 | 0.81 | TAS2R14 (0.48) | RXFP1TRPV1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7203936 | 0.79 | TAS2R14 (0.47) | RXFP1TRPV1MEN1KMT2AMAPT | |
| SCHEMBL6716918 | 0.78 | TRPV1 (0.49) | RXFP1TRPV1MEN1KMT2AMAPT | |
| SCHEMBL7167697 | 0.78 | GRIK1 (0.52) | RXFP1TRPV1MEN1KMT2AMAPT | |
| SCHEMBL6716960 | 0.77 | KMT2A (0.60) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL6728898 | 0.76 | GRIK1 (0.58) | RXFP1TRPV1MEN1KMT2AMAPT | |
| SCHEMBL7378805 | 0.76 | RXFP1 (0.48) | RXFP1TRPV1MEN1KMT2ANPY5R | |
| SCHEMBL2288364 | 0.74 | MAPT (0.64) | MEN1KMT2AMAPTRAB9AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190976-A | Neuroprotective | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND UNIVERSITY OF OREGON (US) | 1993-03-02 | — | — | US | disclosed |