SCHEMBL7381920

SCHEMBL7381920

CCNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 4/20 0.46
MAPT P10636 1/20 0.45
SLC7A5 Q01650 1/20 0.42
ALDH1A1 P00352 2/20 0.42
MMP3 P08254 1/20 0.41
LAP3 P28838 3/20 0.41
ANPEP P15144 2/20 0.40
RNPEP Q9H4A4 2/20 0.40
DNPEP Q9ULA0 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
KMT2A Q03164 1/20 0.40
BIRC2 Q13490 1/20 0.39
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
MMP2 P08253 2/20 0.39
MMP9 P14780 2/20 0.39
MMP8 P22894 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11078076 0.85 SLC7A5 (0.52) MAPTSLC7A5ANPEPRNPEPDNPEP
SCHEMBL11078078 0.85 SLC7A5 (0.52) MAPTSLC7A5ANPEPRNPEPDNPEP
SCHEMBL10018034 0.85 CAPN1 (0.48) CAPN1MAPTANPEPRNPEPDNPEP
SCHEMBL1019805 0.84 ALDH1A1 (0.56) MAPTSLC7A5ALDH1A1LAP3MEN1
SCHEMBL1019806 0.84 ALDH1A1 (0.56) MAPTSLC7A5ALDH1A1LAP3MEN1
SCHEMBL1021759 0.84 ALDH1A1 (0.56) MAPTSLC7A5ALDH1A1LAP3MEN1
SCHEMBL2722882 0.84 ALDH1A1 (0.56) MAPTSLC7A5ALDH1A1LAP3MEN1
SCHEMBL2722888 0.84 ALDH1A1 (0.56) MAPTSLC7A5ALDH1A1LAP3MEN1
SCHEMBL30543983 0.84 ALDH1A1 (0.56) MAPTSLC7A5ALDH1A1LAP3MEN1
Leu-Leu SCHEMBL6044006 0.84 ALDH1A1 (0.60) MAPTSLC7A5ALDH1A1LAP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1183241-A1 SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM Aventis Pharma Deutschland GmbH (DE) 2002-03-06 EP disclosed
WO-2000069831-A1 SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2000-11-23 WO disclosed
EP-0946166-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING WARNER-LAMBERT COMPANY (US) 1999-10-06 EP disclosed
WO-1998026773-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING WARNER-LAMBERT COMPANY (US) 1998-06-25 WO disclosed