SCHEMBL11078076

SCHEMBL11078076

CCNC(=O)C(N)CC(C)C

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.52
ANPEP P15144 3/20 0.47
RNPEP Q9H4A4 2/20 0.47
DNPEP Q9ULA0 2/20 0.47
LARS1 Q9P2J5 3/20 0.44
AAK1 Q2M2I8 1/20 0.41
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
DPP7 Q9UHL4 2/20 0.40
MAPT P10636 1/20 0.40
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
RRM1 P23921 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11078078 1.00 SLC7A5 (0.52) SLC7A5ANPEPRNPEPDNPEPLARS1
SCHEMBL7381920 0.85 CAPN1 (0.46) SLC7A5ANPEPRNPEPDNPEPMAPT
SCHEMBL13789959 0.84 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPLARS1
SCHEMBL6507884 0.83 DPP7 (0.50) SLC7A5ANPEPRNPEPDNPEPLARS1
SCHEMBL8768451 0.83 SLC7A5 (0.52) SLC7A5ANPEPRNPEPDNPEPLARS1
Hydrochloric Acid SCHEMBL8624056 0.83 SLC7A5 (0.52) SLC7A5ANPEPRNPEPDNPEPLARS1
Hydrochloric Acid SCHEMBL8624053 0.83 SLC7A5 (0.52) SLC7A5ANPEPRNPEPDNPEPLARS1
SCHEMBL25328112 0.81 SLC7A5 (0.50) SLC7A5ANPEPRNPEPDNPEPLARS1
SCHEMBL9113004 0.81 DPP7 (0.52) SLC7A5ANPEPRNPEPDNPEPLARS1
SCHEMBL830163 0.80 SLC7A5 (0.45) SLC7A5ANPEPRNPEPDNPEPLARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220025370-A1 OLIGOMER-CONJUGATE COMPLEXES AND THEIR USE IONIS PHARMACEUTICALS, INC. (US) 2022-01-27 US disclosed
US-20170066787-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2017-03-09 US disclosed
US-9572823-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-21 US disclosed
US-20110263539-A1 SHIP 1 MODULATOR COMPOUNDS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2011-10-27 US disclosed
US-20100323990-A1 SHIP 1 MODULATOR PRODRUGS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2010-12-23 US disclosed
US-4483988-A Substituted derivatives of 4-t-alkoxycarbonyl-piperazin-2-ones RICHARDSON MERRELL INC. (US) 1984-11-20 US disclosed
US-4435571-A 5-(Substituted benzyl)-6-oxo-2-piperazine carboxylic acids and esters RICHARDSON MERRELL INC. (US) 1984-03-06 US disclosed
US-4341698-A Enkaphalin derivatives RICHARDSON-MERRELL INC. (US) 1982-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100323990-A1 SHIP 1 MODULATOR PRODRUGS PPM1D, PPM1G, PPM1F SLC7A5 3768/4885ANPEP 4534/4885RNPEP 4693/4885
US-20170066787-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 SLC7A5 45/4885ANPEP 1265/4885RNPEP 1011/4885
US-20220025370-A1 OLIGOMER-CONJUGATE COMPLEXES AND THEIR USE DCLRE1B, NT5C3B, PAICS SLC7A5 2328/4885ANPEP 943/4885RNPEP 603/4885
US-20110263539-A1 SHIP 1 MODULATOR COMPOUNDS PPM1F, PPM1D, PPP1R1B SLC7A5 4451/4885ANPEP 4748/4885RNPEP 4689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.