⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6372249 | 1.00 | — | — | |
| SCHEMBL20760387 | 0.84 | LMNA (0.39) | — | |
| SCHEMBL12882475 | 0.80 | — | — | |
| SCHEMBL2177336 | 0.80 | — | — | |
| SCHEMBL22685065 | 0.78 | — | — | |
| SCHEMBL18858385 | 0.76 | — | — | |
| SCHEMBL14155375 | 0.76 | PPP5C (0.33) | — | |
| SCHEMBL17545529 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL12865446 | 0.73 | — | — | |
| SCHEMBL14971223 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138181-B2 | Imidazo[1,2-a]pyridine compounds as receptor tyrosine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20100029633-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-02-04 | — | — | US | disclosed |