Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.49 |
| ▸ | BHMT | Q93088 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416182 | 1.00 | CDC25B (0.50) | CDC25BSLC15A1BHMTALDH1A1MAPK1 | |
| Methylamine SCHEMBL27674682 | 0.96 | CDC25B (0.47) | CDC25BSLC15A1BHMTALDH1A1MAPK1 | |
| SCHEMBL2679262 | 0.86 | CDC25B (0.52) | CDC25BSLC15A1ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL2679263 | 0.86 | CDC25B (0.52) | CDC25BSLC15A1ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL124385 | 0.81 | SLC15A1 (0.55) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1 | |
| SCHEMBL4850398 | 0.81 | SLC15A1 (0.55) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1 | |
| SCHEMBL432780 | 0.81 | SLC15A1 (0.55) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1 | |
| SCHEMBL10996772 | 0.80 | IDO1 (0.56) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1 | |
| SCHEMBL10996770 | 0.80 | IDO1 (0.56) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1 | |
| Hydrochloric Acid SCHEMBL29398213 | 0.80 | SLC15A1 (0.53) | SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975612-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-0975612-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046582-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-22 | — | — | WO | disclosed |