SCHEMBL7416182

SCHEMBL7416182

N[C@@H](CCSCC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.50
SLC15A1 P46059 2/20 0.49
BHMT Q93088 1/20 0.49
ALDH1A1 P00352 1/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
SLC1A1 P43005 4/20 0.47
SLC1A3 P43003 3/20 0.47
ALPI P09923 1/20 0.45
PKM P14618 1/20 0.45
PTGS1 P23219 1/20 0.45
XIAP P98170 1/20 0.45
SLC7A5 Q01650 1/20 0.45
IDO1 P14902 1/20 0.44
LTA4H P09960 2/20 0.43
SLC1A2 P43004 2/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7382091 1.00 CDC25B (0.50) CDC25BSLC15A1BHMTALDH1A1MAPK1
Methylamine SCHEMBL27674682 0.96 CDC25B (0.47) CDC25BSLC15A1BHMTALDH1A1MAPK1
SCHEMBL2679262 0.86 CDC25B (0.52) CDC25BSLC15A1ALDH1A1MAPK1L3MBTL1
SCHEMBL2679263 0.86 CDC25B (0.52) CDC25BSLC15A1ALDH1A1MAPK1L3MBTL1
SCHEMBL124385 0.81 SLC15A1 (0.55) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL4850398 0.81 SLC15A1 (0.55) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL432780 0.81 SLC15A1 (0.55) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL10996772 0.80 IDO1 (0.56) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL10996770 0.80 IDO1 (0.56) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
Hydrochloric Acid SCHEMBL29398213 0.80 SLC15A1 (0.53) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101481325-A Basic amino acid metalloproteinase inhibitor and use thereof UNIV SHANDONG (CN) 2009-07-15 CN claimed
US-20250057958-A1 CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2025-02-20 US disclosed
US-12187668-B2 Compositions and methods for treating and preventing neurodegenerative disorders ALZHEON, INC. (US) 2025-01-07 US disclosed
EP-3334710-B1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON INC (US) 2023-10-04 EP disclosed
WO-2023161881-A1 CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-08-31 WO disclosed
US-20230133465-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON, INC. 2023-05-04 US disclosed
CN-108026049-B Compositions and methods for treating and preventing neurodegenerative disorders 阿尔泽恩股份有限公司 2021-08-31 CN disclosed
US-11053192-B2 Compositions and methods for treating and preventing neurodegenerative disorders ALZHEON, INC. (US) 2021-07-06 US disclosed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO disclosed
US-20200347012-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON, INC. 2020-11-05 US disclosed
CN-1300303-A Enzyme inhibitors PROCTER & GAMBLE (US) 2001-06-20 CN disclosed
EP-1079821-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2001-03-07 EP disclosed
EP-1025088-A1 IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS AstraZeneca UK Limited (GB) 2000-08-09 EP disclosed
WO-1999059570-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1999-11-25 WO disclosed
WO-1999020611-A1 IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS ZENECA LIMITED (GB) 1999-04-29 WO disclosed
CN-1027640-C Process for producing novel trifluoromethyl ketone substituted peptide derivatives ICI AMERICA INC (US) 1995-02-15 CN disclosed
CN-1019803-B 1,3, the preparation method of 4-thiadiazoles derivative FISONS PLC (GB) 1992-12-30 CN disclosed
CN-87101916-A The preparation method of pharmaceutically active compounds 1988-08-24 CN disclosed
CN-86101066-A Process for producing novel trifluoromethyl ketone substituted peptide derivatives 1986-11-05 CN disclosed
CN-85102340-A The method for preparing immunostimulant acyl tripeptides 1986-10-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230133465-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS PSEN2, CLN6, PSEN1 CDC25B 4245/4885SLC15A1 1805/4885BHMT 53/4885
US-20250057958-A1 CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS CCR2, CCR1, CCRL2 CDC25B 1380/4885SLC15A1 1852/4885BHMT 3019/4885
US-11053192-B2 Compositions and methods for treating and preventing neurodegenerative disorders PSEN2, CLN6, PSEN1 CDC25B 4245/4885SLC15A1 1805/4885BHMT 53/4885
US-12187668-B2 Compositions and methods for treating and preventing neurodegenerative disorders PSEN2, CLN6, PSEN1 CDC25B 4245/4885SLC15A1 1805/4885BHMT 53/4885
US-20200347012-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS PSEN2, CLN6, PSEN1 CDC25B 4245/4885SLC15A1 1805/4885BHMT 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.