Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386048 | 0.88 | FPR2 (0.48) | FPR2NPY1RNPY2RNPC1RAB9A | |
| SCHEMBL7380264 | 0.88 | MEN1 (0.41) | NPC1RAB9AMEN1KMT2ACYP1A2 | |
| SCHEMBL7298366 | 0.86 | KMT2A (0.45) | NPY1RNPY2RNPC1RAB9AMEN1 | |
| SCHEMBL7298373 | 0.86 | KMT2A (0.45) | NPY1RNPY2RNPC1RAB9AMEN1 | |
| SCHEMBL7381948 | 0.86 | CYP1A2 (0.46) | NPC1RAB9AMEN1KMT2ACYP1A2 | |
| SCHEMBL7383064 | 0.85 | FPR2 (0.46) | FPR2NPY1RNPY2RNPC1RAB9A | |
| SCHEMBL10522272 | 0.85 | KMT2A (0.44) | NPY1RNPY2RNPC1RAB9AMEN1 | |
| SCHEMBL7383121 | 0.83 | TDP1 (0.45) | NPY1RNPY2RNPC1RAB9AMEN1 | |
| SCHEMBL7377136 | 0.83 | MEN1 (0.44) | NPC1RAB9AMEN1KMT2ACYP1A2 | |
| SCHEMBL7383128 | 0.83 | MAPT (0.53) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853476-A | Phosphorus containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |