SCHEMBL738284

SCHEMBL738284

O=C(c1ccc(C=NO)cc1)N1CCCCC1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 9/20 0.67
ALDH1A1 P00352 3/20 0.67
KMT2A Q03164 2/20 0.53
TSHR P16473 2/20 0.53
MEN1 O00255 1/20 0.53
MAPK1 P28482 1/20 0.51
CA12 O43570 2/20 0.51
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA7 P43166 2/20 0.51
CA9 Q16790 2/20 0.51
CA14 Q9ULX7 2/20 0.51
MLYCD O95822 2/20 0.50
MAPT P10636 1/20 0.50
USP2 O75604 1/20 0.50
LMNA P02545 1/20 0.50
MAOA P21397 1/20 0.49
MBTD1 Q05BQ5 2/20 0.49
L3MBTL3 Q96JM7 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27479149 0.82 HPGD (1.00) HPGDALDH1A1KMT2ATSHRMEN1
SCHEMBL7132525 0.82 HPGD (1.00) HPGDALDH1A1KMT2ATSHRMEN1
SCHEMBL6617073 0.81 HPGD (0.74) HPGDALDH1A1KMT2ATSHRMEN1
SCHEMBL10721733 0.80 HPGD (0.95) HPGDALDH1A1KMT2ATSHRMEN1
SCHEMBL4900673 0.79 HPGD (0.71) HPGDALDH1A1KMT2ATSHRMEN1
SCHEMBL6223960 0.79 HPGD (0.70) HPGDALDH1A1KMT2ATSHRMEN1
SCHEMBL22345351 0.77 L3MBTL3 (0.47) ALDH1A1KMT2AMBTD1L3MBTL3L3MBTL1
SCHEMBL22345350 0.77 L3MBTL3 (0.47) ALDH1A1KMT2AMBTD1L3MBTL3L3MBTL1
SCHEMBL13578497 0.75 HPGD (0.70) HPGDALDH1A1KMT2ATSHRMEN1
SCHEMBL4050706 0.74 HPGD (0.83) HPGDALDH1A1KMT2ATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387451-A1 ORAL FELINE FEED AND METHODS FOR CONTROLLING TICK INFESTATIONS IN A FELINE In the Bowl Animal Health, Inc. (US) 2024-06-26 EP disclosed
US-20240165085-A1 ORAL FELINE FEED AND METHODS FOR CONTROLLING TICK INFESTATIONS IN A FELINE IN THE BOWL ANIMAL HEALTH, INC. 2024-05-23 US disclosed
US-20240156789-A1 ORAL FELINE FEED AND METHODS FOR CONTROLLING FLEA INFESTATIONS IN A FELINE IN THE BOWL ANIMAL HEALTH, INC. 2024-05-16 US disclosed
EP-4358737-A2 ORAL FELINE FEED AND METHODS FOR CONTROLLING FLEA INFESTATIONS IN A FELINE In the Bowl Animal Health, Inc. (US) 2024-05-01 EP disclosed
CN-117915782-A Oral feed for felines and method for controlling flea infestations in felines 碗中动物健康公司 2024-04-19 CN disclosed
CN-117769356-A Oral feed for felines and method for controlling tick infestations in felines 碗中动物健康公司 2024-03-26 CN disclosed
CN-117500498-A Method for controlling flea and tick infestations in mammals 碗中动物健康公司 2024-02-02 CN disclosed
EP-4304356-A1 ORAL CANINE FEED AND METHODS FOR CONTROLLING FLEA INFESTATIONS IN A CANINE In the Bowl Animal Health, Inc. (US) 2024-01-17 EP disclosed
EP-4304357-A1 ORAL CANINE FEED AND METHODS FOR CONTROLLING TICK INFESTATIONS IN A CANINE In the Bowl Animal Health, Inc. (US) 2024-01-17 EP disclosed
EP-4304722-A1 METHODS FOR CONTROLLING FLEA AND TICK INFESTATIONS IN A MAMMAL In the Bowl Animal Health, Inc. (US) 2024-01-17 EP disclosed
US-20130296559-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE NISSAN CHEMICAL CORPORATION (JP) 2013-11-07 US disclosed
US-8492311-B2 Isoxazoline-substituted benzamide compound and pesticide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-07-23 US disclosed
US-20120172615-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-07-05 US disclosed
US-8138213-B2 Isoxazoline-substituted benzamide compound and pesticide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-20 US disclosed
US-20110251398-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-10-13 US disclosed
US-8022089-B2 Isoxazoline-substituted benzamide compound and pesticide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-09-20 US disclosed
US-7662972-B2 Isoxazoline-substituted benzamide compound and pesticide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-02-16 US disclosed
US-20090312330-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-12-17 US disclosed
US-20070066617-A1 Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-22 US disclosed
EP-1731512-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT Nissan Chemical Industries, Ltd. (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172615-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE C3AR1, C5, C9 HPGD 4108/4885ALDH1A1 3702/4885KMT2A 2864/4885
US-20240156789-A1 ORAL FELINE FEED AND METHODS FOR CONTROLLING FLEA INFESTATIONS IN A FELINE CAT, F7, PIGO HPGD 3181/4885ALDH1A1 1101/4885KMT2A 1024/4885
US-20090312330-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE ATM, CHRM1, NAT1 HPGD 4110/4885ALDH1A1 806/4885KMT2A 1871/4885
US-20240165085-A1 ORAL FELINE FEED AND METHODS FOR CONTROLLING TICK INFESTATIONS IN A FELINE CAT, F7, PIGO HPGD 3557/4885ALDH1A1 1377/4885KMT2A 1013/4885
US-20130296559-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE C5, C3AR1, C9 HPGD 3968/4885ALDH1A1 3329/4885KMT2A 2734/4885
US-20110251398-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE CBR3, CHRM1, CBR1 HPGD 4338/4885ALDH1A1 1983/4885KMT2A 3427/4885
US-20070066617-A1 Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly CHRM1, DDT, ATM HPGD 4252/4885ALDH1A1 1359/4885KMT2A 3861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.