SCHEMBL4900673

SCHEMBL4900673

C=Cc1ccc(C(=O)N2CCCCC2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 10/20 0.71
ALDH1A1 P00352 4/20 0.71
TSHR P16473 2/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
MAPK1 P28482 1/20 0.54
CA12 O43570 2/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA7 P43166 2/20 0.54
CA9 Q16790 2/20 0.54
CA14 Q9ULX7 2/20 0.54
MLYCD O95822 2/20 0.53
USP2 O75604 1/20 0.53
LMNA P02545 2/20 0.53
MAPT P10636 1/20 0.53
HTT P42858 1/20 0.52
MBTD1 Q05BQ5 3/20 0.51
L3MBTL3 Q96JM7 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27479149 0.84 HPGD (1.00) HPGDALDH1A1TSHRMEN1KMT2A
SCHEMBL7132525 0.84 HPGD (1.00) HPGDALDH1A1TSHRMEN1KMT2A
SCHEMBL6617073 0.84 HPGD (0.74) HPGDALDH1A1TSHRMEN1KMT2A
SCHEMBL4906405 0.83 PHGDH (0.63) HPGDALDH1A1TSHRKMT2AMAPK1
SCHEMBL8140738 0.83 ALDH1A1 (0.47) HPGDALDH1A1MEN1KMT2ACA12
SCHEMBL395217 0.83 POLB (0.63) HPGDTSHRMEN1KMT2ALMNA
SCHEMBL10721733 0.82 HPGD (0.95) HPGDALDH1A1TSHRMEN1KMT2A
SCHEMBL21078281 0.82 HPGD (0.48) HPGDALDH1A1TSHRMEN1KMT2A
SCHEMBL6223960 0.81 HPGD (0.70) HPGDALDH1A1TSHRMEN1KMT2A
SCHEMBL5763334 0.80 HPGD (0.62) HPGDALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117651696-A Vinyl thianthrene onium compounds, method for the production thereof and use thereof for transferring vinyl groups 科勒研究非盈利有限责任公司 2024-03-05 CN disclosed
WO-2023280638-A1 VINYL THIANTHRENIUM COMPOUND, PROCESS FOR ITS PREPARATION AND ITS USE FOR TRANSFERRING A VINYL GROUP STUDIENGESELLSCHAFT KOHLE MBH (DE) 2023-01-12 WO disclosed
EP-4112600-A1 VINYL THIANTHRENIUM COMPOUND, PROCESS FOR ITS PREPARATION AND ITS USE FOR TRANSFERRING A VINYL GROUP Studiengesellschaft Kohle mbH (DE) 2023-01-04 EP disclosed
US-20080003288-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2008-01-03 US disclosed
US-7204997-B2 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2007-04-17 US disclosed
EP-1478403-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA, INC. (CA) 2004-11-24 EP disclosed
US-20030152623-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2003-08-14 US disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed