Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.44 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 3/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384921 | 0.98 | CTSK (0.45) | CTSKCTSLCTSSCTSBREN | |
| SCHEMBL7432731 | 0.94 | CTSK (0.46) | CTSKCTSLCTSSCTSBREN | |
| SCHEMBL7383160 | 0.94 | CTSK (0.42) | CTSKCTSLCTSSCTSBREN | |
| SCHEMBL7382553 | 0.92 | CTSK (0.42) | CTSKCTSLCTSSCTSBREN | |
| SCHEMBL7385853 | 0.88 | CTSK (0.43) | CTSKCTSLCTSSCTSBREN | |
| SCHEMBL7425528 | 0.86 | CTSK (0.42) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7377812 | 0.85 | CTSK (0.44) | CTSKCTSLCTSSCTSBREN | |
| SCHEMBL7384528 | 0.85 | CTSK (0.43) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7382133 | 0.84 | REN (0.47) | CTSKCTSBREN | |
| SCHEMBL7382221 | 0.82 | CTSK (0.41) | CTSKCTSLCTSSCTSBREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946166-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998026773-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |