Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383193 | 1.00 | MTNR1A (0.51) | MTNR1AMTNR1BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5370545 | 0.88 | MTNR1A (0.63) | MTNR1AMTNR1BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5370551 | 0.88 | MTNR1A (0.63) | MTNR1AMTNR1BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9030834 | 0.83 | FFAR1 (0.48) | SSTR4 | |
| SCHEMBL9030828 | 0.83 | FFAR1 (0.48) | SSTR4 | |
| SCHEMBL6176229 | 0.82 | AAK1 (0.48) | MTNR1AMTNR1BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6176223 | 0.82 | AAK1 (0.48) | MTNR1AMTNR1BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5430975 | 0.77 | KMT2A (0.39) | MTNR1AMTNR1BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5371265 | 0.76 | KMT2A (0.48) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL5371269 | 0.76 | KMT2A (0.48) | KMT2AMEN1SMN1; SMN2GAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998011112-A1 | TRICYCLIC INDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SYNTHELABO (FR) | 1998-03-19 | — | — | WO | disclosed |