SCHEMBL9030834

SCHEMBL9030834

CC(COc1cc(F)ccc1Br)NC(=O)O

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
PKM P14618 1/20 0.43
SSTR4 P31391 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9030828 1.00 FFAR1 (0.48) FFAR1FFAR4PKMSSTR4
SCHEMBL7383196 0.83 MTNR1A (0.51) SSTR4
SCHEMBL7383193 0.83 MTNR1A (0.51) SSTR4
SCHEMBL9110740 0.81 MTNR1A (0.47)
SCHEMBL12814339 0.79 MRGPRX4 (0.49)
SCHEMBL14300877 0.78 FFAR1 (0.46) FFAR1FFAR4PKM
SCHEMBL12388688 0.78 FFAR1 (0.44) FFAR1FFAR4PKM
SCHEMBL14631808 0.76 RAB9A (0.37) PKM
SCHEMBL9029523 0.76 FFAR1 (0.45) FFAR1FFAR4PKM
SCHEMBL9029531 0.76 FFAR1 (0.45) FFAR1FFAR4PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0732334-A1 Piperidine derivatives, process for their preparation and their therapeutic application SYNTHELABO (FR) 1996-09-18 EP disclosed