Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13336863 | 0.87 | FGFR3 (0.76) | FGFR3KDR | |
| SCHEMBL71926 | 0.86 | FGFR3 (0.77) | FGFR3KDR | |
| SCHEMBL3322732 | 0.86 | FGFR3 (0.75) | FGFR3KDR | |
| SCHEMBL72789 | 0.85 | FYN (0.63) | FGFR3KDR | |
| SCHEMBL11925884 | 0.84 | KDR (1.00) | FGFR3KDR | |
| SCHEMBL3321150 | 0.83 | KDR (0.80) | FGFR3KDR | |
| SCHEMBL3325312 | 0.83 | KDR (0.73) | FGFR3KDR | |
| SCHEMBL11929183 | 0.83 | FGFR3 (0.76) | FGFR3KDR | |
| SCHEMBL13336643 | 0.83 | FGFR3 (0.80) | FGFR3KDR | |
| SCHEMBL3325363 | 0.83 | KDR (0.79) | FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8131527-B1 | FGFR pharmacophore compounds | ASTEX THERAPEUTICS LTD. (GB) | 2012-03-06 | — | — | US | disclosed |
| US-8131527-B1 | FGFR pharmacophore compounds | ASTEX THERAPEUTICS LTD. (GB) | 2012-03-06 | — | — | US | disclosed |