Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383462 | 0.84 | CACNA1B (0.64) | CACNA1BALDH1A1KMT2A | |
| SCHEMBL7391056 | 0.80 | CACNA1B (0.43) | CACNA1BALDH1A1OPRM1 | |
| SCHEMBL7380663 | 0.78 | CACNA1B (0.45) | CACNA1BALDH1A1MAOBOPRM1 | |
| SCHEMBL7351806 | 0.78 | CACNA1B (0.45) | CACNA1BSIGMAR1 | |
| SCHEMBL7421570 | 0.78 | CACNA1B (0.43) | CACNA1BALDH1A1MAOBMAOA | |
| SCHEMBL7429335 | 0.77 | CACNA1B (0.52) | CACNA1BALDH1A1 | |
| SCHEMBL7424188 | 0.77 | CACNA1B (0.58) | CACNA1B | |
| SCHEMBL7383571 | 0.77 | CACNA1B (0.58) | CACNA1B | |
| SCHEMBL7354602 | 0.77 | CACNA1B (0.53) | CACNA1BSIGMAR1MAOBMAOAOPRM1 | |
| SCHEMBL7390855 | 0.76 | CACNA1B (0.44) | CACNA1BOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999043658-A1 | HETEROCYCLIC SUBSTITUTED ANILINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-09-02 | — | — | WO | claimed |
| WO-1999043658-A1 | HETEROCYCLIC SUBSTITUTED ANILINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-09-02 | — | — | WO | disclosed |