Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.36 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 6/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | FLT1 | P17948 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 2/20 | 0.32 |
| ▸ | FLT4 | P35916 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.32 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382750 | 0.87 | — | — | |
| SCHEMBL7379461 | 0.81 | — | — | |
| SCHEMBL7375870 | 0.80 | — | — | |
| SCHEMBL7379899 | 0.80 | KLKB1 (0.33) | ROCK1 | |
| SCHEMBL7374815 | 0.73 | SLC22A12 (0.31) | — | |
| SCHEMBL7378268 | 0.73 | CYP2A6 (0.38) | KDRAURKBMAP4K4FGFR1FLT1 | |
| SCHEMBL7368812 | 0.73 | NR4A2 (0.31) | — | |
| SCHEMBL7375448 | 0.73 | NCF1 (0.32) | — | |
| SCHEMBL7379895 | 0.71 | HSP90AB1 (0.35) | — | |
| SCHEMBL7379420 | 0.71 | P2RY12 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944386-A4 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0944386-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025611-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-18 | — | — | WO | disclosed |