Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488669 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4ETSHR | |
| SCHEMBL7418818 | 0.75 | KDM4E (0.30) | ALDH1A1KDM4E | |
| SCHEMBL7417758 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KDM4E | |
| SCHEMBL7496506 | 0.70 | MEN1 (0.33) | — | |
| SCHEMBL7496602 | 0.70 | KCNH2 (0.34) | ALDH1A1 | |
| SCHEMBL554194 | 0.66 | MAPT (0.33) | ALDH1A1ACE | |
| SCHEMBL554193 | 0.66 | MAPT (0.33) | ALDH1A1KDM4EACE | |
| SCHEMBL7051453 | 0.64 | ALDH1A1 (0.41) | ALDH1A1ACE | |
| SCHEMBL7414641 | 0.63 | CA1 (0.36) | ALDH1A1PDK1 | |
| SCHEMBL9643825 | 0.63 | KMT2A (0.43) | ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929547-B1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLIC AMINO ACID OR CYCL IC HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AG (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-6265404-B1 | FACTOR X INHIBITOR | BERLEX LABORATORIES, INC. | 2001-07-24 | — | — | US | disclosed |
| US-6232325-B1 | THROMBOSIS THERAPY | BERLEX LABORATORIES, INC. | 2001-05-15 | — | — | US | disclosed |
| US-6177473-B1 | FACTOR X INHIBITOR | BERLEX LABORATORIES, INC. | 2001-01-23 | — | — | US | disclosed |
| US-6008234-A | TREATING A HUMAN HAVING A DISEASE-STATE CHARACTERIZED BY THROMBOTIC ACTIVITY, INHIBITING HUMAN BLOOD COAGULATION FACTOR XA | BERLEX LABORATORIES, INC. (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0929547-A1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLIC AMINO ACID OR CYCL IC HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998011094-A1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLIC AMINO ACID OR CYCL IC HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-03-19 | — | — | WO | disclosed |