Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.36 |
| ▸ | CA2 | P00918 | 10/20 | 0.36 |
| ▸ | CA9 | Q16790 | 8/20 | 0.36 |
| ▸ | CA12 | O43570 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380181 | 0.90 | P2RX3 (0.36) | ALDH1A1CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL7385653 | 0.84 | MAPT (0.39) | ALDH1A1CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL7414410 | 0.81 | ALDH1A1 (0.34) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL7381438 | 0.81 | ALDH1A1 (0.36) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL7484832 | 0.70 | TAS1R3 (0.34) | ALDH1A1CYP2D6CYP2C19MAPTPKM | |
| SCHEMBL7486849 | 0.70 | MAPT (0.32) | ALDH1A1CYP2D6CYP2C19MAPTPKM | |
| SCHEMBL7496506 | 0.70 | MEN1 (0.33) | CA1CA2CA9CA12CYP2D6 | |
| SCHEMBL8914013 | 0.69 | ALDH1A1 (0.48) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL2705851 | 0.69 | ALDH1A1 (0.48) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL12943060 | 0.69 | ALDH1A1 (0.48) | CA1CA2CA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929547-B1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLIC AMINO ACID OR CYCL IC HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AG (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-6265404-B1 | FACTOR X INHIBITOR | BERLEX LABORATORIES, INC. | 2001-07-24 | — | — | US | disclosed |
| US-6232325-B1 | THROMBOSIS THERAPY | BERLEX LABORATORIES, INC. | 2001-05-15 | — | — | US | disclosed |
| US-6177473-B1 | FACTOR X INHIBITOR | BERLEX LABORATORIES, INC. | 2001-01-23 | — | — | US | disclosed |
| US-6008234-A | TREATING A HUMAN HAVING A DISEASE-STATE CHARACTERIZED BY THROMBOTIC ACTIVITY, INHIBITING HUMAN BLOOD COAGULATION FACTOR XA | BERLEX LABORATORIES, INC. (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0929547-A1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLIC AMINO ACID OR CYCL IC HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998011094-A1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLIC AMINO ACID OR CYCL IC HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-03-19 | — | — | WO | disclosed |