Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674214 | 0.88 | KCNH2 (0.46) | SIRT2CYP19A1 | |
| SCHEMBL4379824 | 0.86 | SIRT2 (0.43) | ALDH1A1SMN1; SMN2KDM4ELMNASIRT2 | |
| SCHEMBL7668533 | 0.83 | SIRT2 (0.43) | ALDH1A1SMN1; SMN2KDM4ELMNARAB9A | |
| SCHEMBL7844409 | 0.79 | ALOX5 (0.52) | RAB9AMEN1KMT2ASIRT2 | |
| SCHEMBL7818117 | 0.78 | SIRT2 (0.44) | SMN1; SMN2KDM4ERAB9ASIRT2CYP19A1 | |
| SCHEMBL14289994 | 0.76 | SIRT2 (0.46) | SIRT2 | |
| SCHEMBL5891927 | 0.76 | SIRT2 (0.46) | SMN1; SMN2LMNARAB9AMEN1KMT2A | |
| SCHEMBL10818574 | 0.76 | SIRT2 (0.43) | SIRT2 | |
| SCHEMBL5203299 | 0.76 | MAOB (0.50) | SIRT2 | |
| SCHEMBL224236 | 0.75 | SIRT2 (0.43) | SIRT2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962695-A | ANTICOAGULANT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5866577-A | AN ANTICOAGULANT AGENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5620991-A | ANTICOAGULANTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |