Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465079 | 0.86 | KDM4E (0.60) | KDM4ECRHBPCRHR2KMT2AGAA | |
| SCHEMBL7380843 | 0.81 | KDM4E (0.54) | KDM4ECRHBPCRHR2KMT2AGAA | |
| SCHEMBL9176990 | 0.80 | KDM4E (0.64) | KDM4ECRHBPCRHR2KMT2AGAA | |
| SCHEMBL3021147 | 0.69 | AKR1C2 (0.61) | KDM4EKMT2AGAAGHSRPTGS2 | |
| SCHEMBL29799131 | 0.69 | KIF11 (0.66) | KDM4ECRHBPCRHR2KMT2AGAA | |
| SCHEMBL3428313 | 0.69 | KDM4E (0.61) | KDM4EHDAC1HDAC2KMT2AGAA | |
| SCHEMBL2539400 | 0.68 | KDM4E (0.58) | KDM4ECRHBPCRHR2KMT2AGAA | |
| SCHEMBL12075217 | 0.68 | KDM4E (0.61) | KDM4ECRHBPCRHR2KMT2AGAA | |
| Lithium Ion SCHEMBL3428310 | 0.68 | KDM4E (0.56) | KDM4ECRHBPCRHR2HDAC1HDAC2 | |
| SCHEMBL28207430 | 0.67 | KDM4E (0.53) | KDM4ECRHBPCRHR2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069827-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | DARWIN DISCOVERY LIMITED (GB) | 2000-11-23 | — | — | WO | claimed |