Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425249 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL7465079 | 0.84 | KDM4E (0.60) | KDM4ECRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL9176990 | 0.83 | KDM4E (0.64) | KDM4ECRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL7384304 | 0.81 | KDM4E (0.56) | KDM4ECRHBPCRHR2ALDH1A1HSD17B10 | |
| SCHEMBL3935995 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL21430761 | 0.74 | GAA (0.55) | KDM4ECRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL14829878 | 0.74 | GAA (0.51) | KDM4ECRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL6923876 | 0.73 | KDM4E (0.69) | KDM4ECRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL17600647 | 0.73 | ALDH1A1 (0.57) | KDM4ECRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL385458 | 0.73 | ALDH1A1 (0.57) | KDM4ECRHBPCRHR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069827-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | DARWIN DISCOVERY LIMITED (GB) | 2000-11-23 | — | — | WO | disclosed |