Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 14/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762282 | 0.94 | CYP3A4 (0.43) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL7377048 | 0.91 | CTSK (0.41) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL7380606 | 0.89 | CTSK (0.40) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL7384005 | 0.86 | CTSK (0.41) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL7382469 | 0.86 | CTSL (0.38) | ELANECTSLCTSBCTSSCTSK | |
| SCHEMBL7424322 | 0.83 | CTSK (0.42) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL7381006 | 0.83 | CTSK (0.39) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL7381556 | 0.82 | NMBR (0.41) | CTSBCTSK | |
| SCHEMBL7384879 | 0.80 | CTSK (0.41) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL7381284 | 0.78 | CTSK (0.41) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047450-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 2000-11-02 | — | — | EP | disclosed |
| EP-0946166-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1999032150-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |
| WO-1998026773-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |