Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384730 | 1.00 | AGTR2 (0.79) | AGTR2TACR1 | |
| SCHEMBL7389160 | 1.00 | AGTR2 (0.79) | AGTR2TACR1 | |
| SCHEMBL7389164 | 1.00 | AGTR2 (0.79) | AGTR2TACR1 | |
| SCHEMBL7941433 | 0.89 | AGTR2 (1.00) | AGTR2TACR1 | |
| SCHEMBL3516084 | 0.89 | AGTR2 (1.00) | AGTR2TACR1 | |
| SCHEMBL7383952 | 0.86 | TACR1 (0.83) | TACR1 | |
| SCHEMBL3514054 | 0.86 | TACR1 (0.83) | TACR1 | |
| SCHEMBL7387479 | 0.86 | AGTR2 (0.57) | AGTR2TACR1 | |
| SCHEMBL5034004 | 0.86 | AGTR2 (0.57) | AGTR2TACR1 | |
| SCHEMBL7932680 | 0.83 | TACR1 (0.80) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000498-A1 | N,N-DIACYLPIPERAZINES | MERCK & CO., INC. (US) | 1995-01-05 | — | — | WO | disclosed |
| US-5348955-A | Angiotensis II antagonists | MERCK & CO., INC. (US) | 1994-09-20 | — | — | US | disclosed |
| US-5292726-A | N,N-diacylpiperazines | MERCK & CO., INC. (US) | 1994-03-08 | — | — | US | disclosed |
| WO-1992020661-A1 | N, N-DIACYLPIPERAZINES | MERCK & CO., INC. (US) | 1992-11-26 | — | — | WO | disclosed |